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. 2021 Aug 31;15:379–397. doi: 10.2147/BTT.S259124

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© 2021 Abdul Kareem et al.

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Secretome of stem cells.

Notes: Supernatant media of stem cell cultures contains growth factors, cytokines, chemokines and extracellular vesicles that can be purified using ultra-centrifugation filtration units and provide the opportunity to select for certain secretome molecules based on their molecular weights. Secretome of stem cells provides a cell-free universal therapeutic option for wound healing that can potentially have the same benefit as cells but negates the challenges with viability and immune rejection.