Table 3.
List of mutations seen in the three samples.
| Position | Gene | Amino acid change | 1st_breakthrough | 2nd_breakthrough | Index case |
|---|---|---|---|---|---|
| C241T | 5'UTR | NA | |||
| C1267T | ORF1a | G334G | |||
| C2449T | G728G | ||||
| C3037T | F924F | ||||
| C3267T | T1001I | ||||
| C5184T | P1640L | ||||
| C1191T | P309L | ||||
| C5388A | A1708D | ||||
| C6539T | H2092Y | ||||
| C9891T | A3029V | ||||
| GTCTGGTTTT11287G | GTCTGGTTTT->G | ||||
| T11418C | V3718A | ||||
| G11521T | M3752I | ||||
| T12946C | Y4227Y | ||||
| C12970T | N4235N | ||||
| C14408T | ORF1b | P314L | |||
| C14676T | P403P | ||||
| C15279T | H604H | ||||
| T16176C | T903T | ||||
| C16466T | P1000L | ||||
| A20262G | L2265L | ||||
| C21575T | S | L5F | |||
| C21618G | T19R | ||||
| ATACATG21764A | ATACATG->A | ||||
| TTTA21990T | TTTA->T | ||||
| T22917G | L425R | ||||
| C22995A | T478K | ||||
| A23063T | N501Y | ||||
| C23271A | A570D | ||||
| A23403G | D614G | ||||
| C23604G | P681R | ||||
| G24410A | D950N | ||||
| T24506G | S982A | ||||
| C24745T | V1061V | ||||
| G24914C | D1118H | ||||
| C25469T | ORF3 | S26L | |||
| T26767C,G | M | V82A | |||
| A28111G | ORF8 | Y73C | |||
| AGATTTC28247A | AGATTTC->A | ||||
| GAT28280CTA | N | D3L | |||
| A28461G | D63G | ||||
| G28881T | R203M | ||||
| G29402T | D377Y | ||||
| G29427A | R385K |
The colors highlight the presence of mutation.