TABLE 1.
Comparison of demographic and laboratory parameters of AS patients and controls
| Items | AS (N = 136) | Control (N = 63) | t/χ2/Z | p value |
|---|---|---|---|---|
| Age (year) | 33.00 (27.00, 42.00) | 34.00 (28.00, 44.00) | −0.741 | 0.458 |
| Sex, No. (%) | ||||
| Female | 18 (13.24) | 15 (23.81) | 3.480 | 0.062 |
| Male | 118 (86.76) | 48 (76.19) | ||
| WBC (×109/L) | 6.95 ± 1.57 | 6.36 ± 1.20 | 2.635 | 0.009 |
| Neutrophils (×109/L) | 4.05 (3.34, 5.00) | 3.42 (3.02, 4.20) | −3.854 | <0.001 |
| Lymphocytes (×109/L) | 1.97 (1.67, 2.38) | 2.27 (2.00, 2.61) | −2.814 | 0.005 |
| Monocytes (×109/L) | 0.44 (0.35, 0.54) | 0.37 (0.31, 0.43) | −4.148 | <0.001 |
| RDW (%) | 13.30 (12.70, 14.20) | 12.80 (12.60, 13.50) | −3.123 | 0.002 |
| PLT (×109/L) | 245.40 ± 56.98 | 193.17 ± 47.65 | 6.321 | <0.001 |
| NLR | 2.02 (1.57, 2.66) | 1.54 (1.31, 1.90) | −11.337 | <0.001 |
| PLR | 116.18 (92.72, 156.08) | 86.72 (70.97, 106.74) | −11.337 | <0.001 |
| SII (×109/L) | 482.86 (329.60, 661.93) | 308.00 (217.32, 365.45) | −6.801 | <0.001 |
| CRP (mg/L) | 16.45 (8.58, 32.40) | – | – | – |
| ESR (mm/h) | 17.50 (9.00, 36.50) | – | – | – |
| BASDAI | 3.80 (3.30, 4.50) | – | – | – |
| HLA‐B27 positive rate, No. (%) | 110 (80.88) | – | – | – |
| Disease duration (year) | 4.50 (2.00, 10.00) | – | – | – |
Abbreviations: AS, ankylosing spondylitis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CRP, C‐reactive protein; ESR, erythrocyte sedimentation rate; HLA, human leukocyte antigen; NLR,neutrophil‐to‐lymphocyte ratio; PLR, platelet‐to‐lymphocyte ratio; PLT, platelet; RDW, red blood distribution width; SII, systemic immune‐inflammation index; WBC, white blood cell.