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. 2021 Jul 31;35(9):e23934. doi: 10.1002/jcla.23934

TABLE 2.

Study quality of the diagnostic studies, as judged by the QUADAS‐2 checklist

Study Risk of bias Applicability concerns
Patient selection Index Test Reference standard Flow and timing Patient Selection Index Test Reference Standard
Hu et al.31 graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Li et al.32 graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Li et al.33 graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Liu et al.34 graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg ? ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Xing et al.35 ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Yi et al.36 ? ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Yuan et al.37 ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Zheng et al.38 ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Xiao et al.39 graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Yang et al.40 graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Xu et al.41 graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Yin et al.42 ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg
Lv et al.43 graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg ? graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg graphic file with name JCLA-35-e23934-g006.jpg

Inline graphic = low; Inline graphic = high; ? = unclear.

“Low” means “at low risk of bias” or having “low concern regarding applicability”; “High” means “at risk of bias” or having “concerns regarding applicability”; and “unclear” means insufficient data for judgment.