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. 2021 Aug 8;35(9):e23921. doi: 10.1002/jcla.23921

TABLE 2.

Clinical performance of three immunoassays

Clinical diagnosis Sensitivity Specificity
Positive Negative (95% CI) (95% CI)
D ≥ 14 D < 14 Healthy Other Total D ≥ 14 Total Healthy Other
(n = 126) (n = 47) (n = 98) (n = 53) (n = 173) (n = 126) (n = 151) (n = 98) (n = 53)
Abbott Quant Pos 123 43 1 0 96 97.6 99.3 99.0 100
Neg 3 4 97 53 (91.8–98.4) (93.2–99.5) (96.4–100.0) (94.4–100.0) (93.3–100.0)
DiaSorin TrimericS Pos 122 40 0 0 93.6 96.8 100 100 100
Neg 4 7 98 53 (88.9–96.8) (92.1–99.1) (97.6–100.0) (96.3–100.0) (93.3–100.0)
Roche S Pos 123 43 0 0 96 97.6 100 100 100
Neg 3 4 98 53 (91.9–98.4) (93.2–99.5) (97.6–100.0) (96.3–100.0) (93.0–100.0)
Genscript cPass Pos 123 41 NT NT 94.8 97.6 NT NT NT
Neg 3 6 NT NT (90.4–97.6) (93.2–99.5) NT NT NT

Abbreviations: Abbott Quant, Abbott SARS‐CoV‐2 IgG II Quant; D, days after onset of symptom; DiaSorin TrimericS, DiaSorin LIAISON SARS‐CoV‐2 TrimericS IgG; Genscript cPass, Genscript cPass SARS‐CoV‐2 Neutralization Antibody Detection Kit;NT, not tested; Other, other infection; Roche S, Roche Elecsys anti‐SARS‐CoV‐2 S.