Table 2.
Freezing during conditioned fear (upper panel) and mean extinction freezing (lower panel) was correlated with delta FosB cell counts in forebrain regions. Note positive correlation of freezing with amygdala subdivisions and negative correlations with infralimbic (IL) cortex and hippocampal dentate gyrus (DG)
Fos-BLA | Fos-CeA | Fos-DG | Fos-IL | Fos-PL | Fos-BNST | Fos-NAc | |
---|---|---|---|---|---|---|---|
Freezing (Conditioned Fear) | |||||||
Number of XY Pairs | 23 | 23 | 23 | 23 | 20 | 22 | 22 |
Pearson/Spearman r | 0.4003 | 0.5451 | −0.4191 | −0.3533 | 0.2492 | −0.03004 | −0.3033 |
95% confidence interval | −0.02732 to 0.7041 | 0.1587–0.7867 | −0.7153 to 0.004759 | −0.6754 to 0.08188 | −0.2174 to 0.6231 | −0.4461 to 0.3967 | −0.6428 to 0.1358 |
P value (two-tailed) | 0.0584 | 0.0071 | 0.0465 | 0.0981 | 0.2893 | 0.8944 | 0.1701 |
P value summary | # | * | * | # | ns | ns | ns |
Pearson (normal) or Spearman (Gaussian Approx) | Spearman | Spearman | Spearman | Spearman | Pearson | Pearson | Pearson |
Freezing (Extinction Mean) | |||||||
Number of XY Pairs | 23 | 23 | 23 | 23 | 20 | 22 | 22 |
Pearson/Spearman r | 0.06621 | 0.3221 | −0.4733 | −0.5237 | 0.2317 | −0.135 | −0.248 |
95% confidence interval | −0.3671 to 0.4759 | −0.1168 to 0.6558 | −0.7468 to −0.06293 | −0.7750 to −0.1294 | −0.2483 to 0.6203 | −0.5362 to 0.3160 | −0.6146 to 0.2068 |
P value (two-tailed) | 0.7641 | 0.1339 | 0.0225 | 0.0103 | 0.3257 | 0.5492 | 0.2659 |
P value summary | ns | ns | * | * | ns | ns | ns |
Pearson (normal) or Spearman (Gaussian Approx) | Spearman | Spearman | Spearman | Spearman | Pearson | Pearson | Pearson |
p < 0.05,
p = 0.058 (BLA), p = 0.098 (IL).