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. 2021 Aug 27;2021:9929128. doi: 10.1155/2021/9929128

Table 3.

Recent studies reporting TCM and extracts that can improve the efficiency of MSC transplantation in ischemic stroke models.

Drug name Extraction source Possible mechanisms Animal model Source of MSC Research time References
Salvia miltiorrhiza Salvia miltiorrhiza Bunge Promoting the antiapoptotic ability and survival of MSCs Rat cerebral infarction model Bone marrow (rat) 2018 Kim et al. [80]
Angelica gigas extract Angelica gigas Enhancing neovascularization Rat cerebral infarction model Bone marrow (rat) 2018 Kim et al. [85]
Borneol Artemisia and Dipterocarpaceae Suppressing apoptosis and promoting neurogenesis Mouse cerebral infarction model Fetal mice 2017 Zhang et al. [83]
Astragaloside and baicalin Improving the antiapoptosis and anti-inflammatory ability of MSCs by MAPK/ERK pathway Cell inflammatory model induced by lipopolysaccharide Bone marrow (mice) 2017 Zhu et al. [81]
Buyang Huanwu decoction TCM prescription Augmenting angio-miRNA in MSC-secreted exosomes Rat cerebral infarction model Not mentioned 2015 Yang et al. [78]
Buyang Huanwu decoction TCM prescription Upregulating VEGF and Ki-67 Rat cerebral infarction model Bone marrow (rat) 2010 Zhang et al. [77]