Table 3.
Antibiotic substanceb | blaCTX-M, n = 80a | blaCTX-M-positive ESBL-producers, n = 58a | blaCTX-M-positive non ESBL producers, n = 22a | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S | I | R | S | I | R | S | I | R | ||||||||||
n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | n | % | |
AM | 0 | – | 0 | – | 80 | 100 | 0 | – | 0 | – | 58 | 100 | 0 | – | 0 | – | 22 | 100 |
AMC | 48 | 60 | 9 | 11.3 | 23 | 28.8 | 40 | 69 | 9 | 15.5 | 9 | 15.5 | 8 | 36.4 | 0 | – | 14 | 63.6 |
TZP | 64 | 80 | 9 | 11.3 | 7 | 8.8 | 51 | 87.9 | 6 | 10.3 | 1 | 1.7 | 13 | 59.1 | 3 | 13.6 | 6 | 27.3 |
CAZ | 35 | 43.8 | 1 | 1.3 | 44 | 55 | 27 | 46.6 | 1 | 1.7 | 30 | 51.7 | 8 | 36.4 | 0 | – | 14 | 63.6 |
CTX | 11 | 13.8 | 0 | – | 69 | 86.3 | 0 | – | 0 | – | 58 | 100 | 11 | 50 | 0 | – | 11 | 50 |
FEPc | 37 | 50 | 10 | 13.5 | 27 | 36.5 | 29 | 55.8 | 8 | 15.4 | 15 | 28.8 | 8 | 36.4 | 2 | 9.1 | 12 | 54.5 |
ETP | 77 | 96.3 | 2 | 2.5 | 1 | 1.3 | 57 | 98.3 | 1 | 1.7 | 0 | – | 20 | 90.9 | 1 | 4.5 | 1 | 4.5 |
IPM | 80 | 100 | 0 | – | 0 | – | 58 | 100 | 0 | – | 0 | – | 22 | 100 | 0 | – | 0 | – |
MEM | 80 | 100 | 0 | – | 0 | – | 58 | 100 | 0 | – | 0 | – | 22 | 100 | 0 | – | 0 | – |
AN | 78 | 97.5 | 1 | 1.3 | 1 | 1.3 | 58 | 100 | 0 | – | 0 | – | 20 | 90.9 | 1 | 4.5 | 1 | 4.5 |
GM | 52 | 65 | 3 | 3.8 | 25 | 31.3 | 39 | 67.2 | 1 | 1.7 | 18 | 31 | 13 | 59.1 | 2 | 9.1 | 7 | 31.8 |
CIP | 18 | 22.5 | 1 | 1.3 | 61 | 76.3 | 14 | 24.1 | 1 | 1.7 | 43 | 74.1 | 4 | 18.2 | 0 | – | 18 | 81.8 |
AMC: Amoxicillin/Clavulanic acid; TZP: Piperacillin/Tazobactam; ESBL: extended spectrum beta lactamase; CTX: Cefotaxime; CAZ: Ceftazidime; FEP: Cefepime; AN: Amikacin; CIP: Ciprofloxacin; S: susceptible; I: intermediate; R: resistant
aMay not add up to 100% due to rounding errors to 1 decimal place
bInterpretation of resistance according to the clinical breakpoints of CLSI
c6 missing values for cefepime