Table 4.
Performance of blaCTX-M detection to predict phenotypic resistance of Escherichia coli
| Antibiotic | Sensitivity % (95% CI) |
Specificity % (95% CI) |
PPV % (95% CI) |
NPV % (95% CI) |
|---|---|---|---|---|
| ESBL | 87 (76–93) | 54 (39–68) | 73 (61–82) | 74 (56–87) |
| CTX | 85 (75–92) | 68 (49–82) | 86 (76–93) | 66 (48–80) |
| CAZ | 85 (72–93) | 44 (31–57) | 57 (45–67) | 77 (59–89) |
| FEP | 90 (76–97) | 46 (34–58) | 50 (38–62) | 89 (72–96) |
ESBL: Extended spectrum beta lactamases; CTX: Cefotaxime; CAZ: Ceftazidime; FEP: Cefepime; and CIP: Ciprofloxacin; PPV: positive predictive value; NPV: negative predictive value; 95% CI: 95% confidence interval