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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Acta Neuropathol. 2021 Mar 7;141(5):651–666. doi: 10.1007/s00401-021-02279-2

Figure 4:

Figure 4:

The relative proportions of Rhes phenotypes across tauopathies in the entorhinal cortex (A), CA1 (C), and SFG (D). Diffuse Phenotype is the dominant phenotype, and its relative proportion decreases in tauopathies, most notably in AD, PiD, and PSP. Single-nucleus RNA expression data show a negative trend in the quantity of RASD2 with increasing Braak stages transcripts within two selectively vulnerable excitatory neuron populations, but the groups do not statistically significantly differ from one another (C).