Table 2.
Commonly Occurring (> 10% in any arm) Grade 3+ Adverse Events (AE)
| Arm B (N=70) | Arm C (N=70) | Total (N=140) | |
|---|---|---|---|
| Evaluable for AE Analyses | 64 (91.4%) | 66 (94.3%) | 130 (92.8%) |
| Neutropenia | 50(71.4%) | 47(67.1%) | 97(69.3%) |
| Leukopenia | 45(64.3%) | 41(58.6%) | 86(61.4%) |
| Anemia | 15(21.4%) | 16(22.9%) | 31(22.1%) |
| Dehydration | 17(24.3%) | 11(15.7%) | 28(20%) |
| Esophageal pain | 13(18.6%) | 15(21.4%) | 28(20%) |
| Dysphagia | 14(20%) | 11(15.7%) | 25(17.9%) |
| Lymphopenia | 9(12.9%) | 14(20%) | 23(16.4%) |
| Hypokalaemia | 8(11.4%) | 13(18.6%) | 21(15%) |
| Thrombocytopenia | 10(14.3%) | 11(15.7%) | 21(15%) |
| Nausea | 10(14.3%) | 10(14.3%) | 20(14.3%) |
| Febrile neutropenia | 7(10%) | 9(12.9%) | 16(11.4%) |
| Fatigue | 9(12.9%) | 6(8.6%) | 15(10.7%) |
| Hyponatraemia | 7(10%) | 8(11.4%) | 15(10.7%) |
| Esophagitis | 11(15.7%) | 3(4.3%) | 14(10%) |
| Emesis | 9(12.9%) | 5(7.1%) | 14(10%) |
AE, adverse event