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. 2021 Jun 5;6(9):2261–2269. doi: 10.1016/j.ekir.2021.05.020

Table 3.

Treatment targets for therapy

Variable Nondialysis-dependent chronic kidney disease End-stage kidney disease
Iron deficiency unconditionala TSAT ≤ 20% and/or serum ferritin ≤ 100 ng/ml TSAT ≤ 20% and/or serum ferritin ≤ 200 ng/ml
Iron deficiency conditionalb TSAT ≤ 30% and/or serum ferritin ≤ 500 ng/ml TSAT ≤ 30% and/or serum ferritin ≤ 500 ng/ml
a

Threshold for therapy in iron deficiency anemia under any circumstance.

b

Threshold for therapy in individuals with iron deficiency anemia who are not receiving iron therapy or who require erythropoiesis-stimulating agents if the goal is to raise hemoglobin, reduce the dose of the erythropoiesis-stimulating agent, or reduce the need for blood transfusions.