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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Expert Opin Pharmacother. 2021 Apr 7;22(12):1625–1632. doi: 10.1080/14656566.2021.1912015

Table 2:

Selected Adverse Events for Olaparib and Rucaparib

Olaparib (N = 256)[2, 9] Rucaparib (N = 115)[10]
Adverse Event All Grades (%) Grades ≥ 3 (%) All Grades (%) Grades ≥ 3 (%)
Anemia 199 (46) 55 (21) 50 (43.5) 29 (25.2)
Anorexia 77 (30) 3 (1) 32 (27.8) 2 (1.7)
Asthenia/Fatigue 104 (41) 7 (3) 71 (61.7) 10 (8.7)
Creatinine elevation[8] 9 (18%) 0 (0) 18 (15.7) 1 (0.9)
Diarrhea 54 (21) 2 (<1) 23 (20.0) 0
Nausea 106 (41) 3 (1) 60 (52.2) 3 (2.6)
Neutropenia NR 10 (3.9) 12 (10.4) 8 (7.0)

NR Not reported