Table 4.
Heritability and correlation between traits
| Heritability |
Total P-wave duration | Standardized P-wave duration | Integral of P wave | RMS20 | RMS30 | RMS40 | RMS PW | ||
|---|---|---|---|---|---|---|---|---|---|
| Simple model∗ (%) | Multivariable model† (%) | ||||||||
| Total P-wave duration | 24.6 | 21.6 | — | 0.99 ± 0.01 | 0.20 ± 0.11 | –0.41 ± 0.13 | –0.42 ± 0.13 | –0.29 ± 0.15 | –0.05 ± 0.12 |
| Standardized P-wave duration | 20.8 | 18.0 | 0.93 ± 0.00 | — | 0.14 ± 0.12 | –0.51 ± 0.13 | –0.57 ± 0.12 | –0.42 ± 0.14 | –0.11 ± 0.12 |
| Integral of P-wave | 26.1 | 24.9 | 0.12 ± 0.04 | 0.03 ± 0.04 | — | 0.22 ± 0.03 | 0.38 ± 0.03 | 0.50 ± 0.03 | 0.50 ± 0.03 |
| RMS20 | 15.0 | 14.3 | –0.54 ± 0.03 | –0.52 ± 0.03 | 0.34 ± 0.15 | — | 0.84 ± 0.01 | 0.72 ± 0.02 | 0.34 ± 0.03 |
| RMS30 | 12.7 | 11.9 | –0.49 ± 0.03 | –0.48 ± 0.03 | 0.44 ± 0.14 | 0.98 ± 0.04 | — | 0.89 ± 0.01 | 0.49 ± 0.03 |
| RMS40 | 12.2 | 12.3 | –0.45 ± 0.03 | –0.45 ± 0.03 | 0.72 ± 0.10 | 0.76 ± 0.10 | 0.88 ± 0.05 | — | 0.60 ± 0.02 |
| RMS PW | 24.7 | 23.0 | –0.13 ± 0.04 | –0.19 ± 0.04 | 0.72 ± 0.10 | 0.44 ± 0.14 | 0.56 ± 0.12 | 0.80 ± 0.09 | — |
Values are given as correlation coefficient ± standard error. Upper diagonal shows genetic correlations, and lower shaded diagonal shows environmental correlations.
∗
Simple model: Adjusted for age, sex, and cohort.
†
Multivariable model: Additionally adjusted for height, weight, smoking, systolic and diastolic blood pressure, triglycerides, total/HDL cholesterol, waist circumference, heart rate, moderate/severe alcohol consumption, diabetes, hypertension treatment, prevalent myocardial infarction, prevalent AF, prevalent heart failure, and AV node blockers.