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. Author manuscript; available in PMC: 2022 Sep 2.
Published in final edited form as: Structure. 2021 May 19;29(9):1048–1064.e6. doi: 10.1016/j.str.2021.05.002

Figure 2. The eight distinct clusters resolved by trFRET-DMD.

Figure 2.

(A) Energy versus radius of gyration (Rg) for the structural ensemble and the centroid structures of the eight clusters (C1-8). The structures are colored from red (N-terminus) to blue (C-terminus).

(B) The energy landscapes of α-syn based on RMSD, Rg, and/or potential. RMSD indicates the distance between each structure and the average structure of the conformational ensemble.