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. 2021 May 21;19(9):1559–1570. doi: 10.1158/1541-7786.MCR-20-1017

Table 1.

Conformations of Leu536 observed in high-resolution x-ray crystal structures of ERα.

Individual Position of Leu536
Sequence # Structures Monomers Buried Exposed Unresolved
Wild-type 13 28 5 (17.9%) 23 (82.1%) 0 (0%)
Y537S 170 346 340 (98.3%) 3 (0.9%) 3 (0.9%)
D538G 2 4 4 (100%) 0 (0%) 0 (0%)