Table 1.
Mainstream immune repertoire sequencing productions
| Adaptive Biotechnologies | iRepertoire | BGI | Illumina | Thermo scientific | |
|---|---|---|---|---|---|
| Production | ImmunoSEQ | iR-Harmony | BGISEQ-500 | Illumina HiSeq/MiSeq | Ion AmpliSeq Immune Repertoire |
| TCR/BCR | TCR | TCR/BCR | TCR/BCR | TCR/BCR | TCR |
| Receptor type | β | All (7 chains) | α/β | α/β | β |
| DNA/RNA | DNA/cDNA | DNA/RNA | DNA/RNA | DNA/RNA | RNA |
| Human/Mouse | Human, Mouse | Human, Mouse | Human | Human | Human |
| Amplification method | Multiplex PCR | Multiplex DAM- PCR | Multiplex PCR | Bridge PCR | Multiplex PCR |
| UMIs | No | Yes | No | Yes | No |
| Ref. | 34-37 | 25, 38-40 | 21, 41-44 | 14, 17, 45-48 | 49- 52 |