Table 2.

Common information analysis tools

Tools	File format	TCR/BCR	Run	Programming languages	Maximum input value	Sequence quality	UMIs	Clustering	Ref.
IMGT/HighV-QUEST	FASTA	TCR/BCR	Online	-	150000	NO	NO	Yes	68-70
IgBLAST	FASTA	TCR/BCR	Online/stand-alone	C++	<1000	NO	NO	NO	71
VDJPipe	FASTA	TCR/BCR	Online/stand-alone	C++	None	Yes	Yes	NO	63
MiXCR	FASTA/FASTQ	TCR/BCR	stand-alone	Java	None	Yes	NO	Yes	72
ImmuneDB	FASTA/FASTQ	TCR/BCR	stand-alone	Python	None	Yes	Yes	NO	73
VDJtools	FASTA/FASTQ	TCR	stand-alone	Java/Groovy	None	NO	Yes	Yes	75
VDJServer	FASTA/FASTQ	TCR/BCR	Online	-	None	Yes	Yes	Yes	79
VDJdb	FASTA/FASTQ	TCR	stand-alone	Java	None	Yes	NO	NO	77
TRIg	FASTA	TCR/BCR	stand-alone	Perl	None	NO	NO	NO	87
Vidjil	FASTA/FASTQ	TCR/BCR	stand-alone	C++/Java	None	NO	NO	Yes	78