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. Author manuscript; available in PMC: 2022 Sep 2.
Published in final edited form as: Cell Stem Cell. 2021 May 3;28(9):1597–1613.e7. doi: 10.1016/j.stem.2021.04.011

Figure 5. ScRNA-seq analysis identifies landscape alterations of murine HNSCC upon anti-CD276 treatment.

Figure 5.

(A) UMAP plot showing identified cancer cell populations from two groups merged which were treated with control IgG and anti-CD276 for 4 weeks.

(B) UMAP plot showing distribution of annotated clusters within cancer cells upon control IgG or anti-CD276 treatment for 4 weeks.

(C) Heatmap displaying expression of selected marker genes in each cluster.

(D-I) UMAP plot of tumor cells displaying selected marker gene expression.

(J) Percentage of different cancer cell populations annotated in response of anti-CD276 treatment.

(K) Distribution fraction of different cancer cell populations annotated in response of anti-CD276 treatment.

(L) UMAP plot of Bmi1+ cancer cells upon anti-CD276 treatment.

(M) UMAP plot of Cd276+ cancer cells upon anti-CD276 treatment.

See also Figure S2