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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Mol Cancer Res. 2021 May 13;19(9):1476–1485. doi: 10.1158/1541-7786.MCR-20-0992

Figure 3. FL and dEx1 MAML3 contribute to a more aggressive phenotype in vitro.

Figure 3.

A, All three neuroendocrine tumor cell lines had higher invasion through Matrigel when transfected with either FL or dEx1 MAML3.B, Soft agar colony formation was increased in QGP-1 and BON-1 cell lines transfected with MAML3 FL or dEx1 compared to empty vector controls. SK-N-SH did not retain transient transfection long enough for this assay. C, Cell viability increased in all three cell lines with FL or dEx1 MAML3 transfection. Error bars represent SEM across at least three separate experiments done in at least triplicate for invasion and cell viability, and four separate experiments done in duplicate for colony formation. (* p<0.05, ** p<0.01, *** p<0.001, **** p<0.0001)