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. Author manuscript; available in PMC: 2021 Sep 6.
Published in final edited form as: Mol Cancer Ther. 2021 Jun 22;20(9):1592–1602. doi: 10.1158/1535-7163.MCT-21-0074

Figure 4. Mice implanted with EBV+ human B-cells show significantly increased plasma levels of human Ig κ and λ FLC.

Figure 4.

A, Plasma levels of human Ig κ and B, Ig λ FLC, as measured by ELISA. Results are provided for each experimental group and included are the combined results of two-independent experiments for mice implanted EBV− and EBV+ B-cells, and treated with ch128.1/IgG1 or IgG1 control. Bars are geometric mean values. Also shown are mean values of human Ig κ and λ FLC in healthy human plasma samples (Lab QC). Nonparametric, unpaired Mann-Whitney tests were conducted, where *p = 0.01–0.05, ***p = 0.0001–0.001, ****p < 0.0001, and ns, not significant.