Table 5.

Stratified analysis by H. pylori biomarker status for top associated metabolites

	Omp- and/or HP 0305-, N= 209		Omp+ and HP 0305+, N= 282
Metabolites	OR (95%CI)	P	OR (95%CI)	P	P interaction
orotate	1.97 (1.27–3.05)	0.00237	1.60 (1.15–2.22)	0.00518	0.42924
1-(1-enyl-palmitoyl)-GPE (P-16:0)	1.53 (1.11–2.11)	0.00921	1.65 (1.20–2.27)	0.00196	0.72353
sphinganine	1.51 (1.10–2.05)	0.00998	1.61 (1.15–2.25)	0.00544	0.77056
1-(1-enyl-stearoyl)-GPE (P-18:0)	1.60 (1.13–2.25)	0.00727	1.56 (1.13–2.15)	0.00644	0.91327
glycerophosphoethanolamine	1.58 (1.14–2.20)	0.0067	1.52 (1.09–2.12)	0.01285	0.86561
5alpha-pregnan-3beta,20beta-diol monosulfate	1.43 (1.05–1.95)	0.0225	1.44 (1.07–1.93)	0.01579	0.97956
N6-methyllysine	1.37 (0.99–1.91)	0.06112	1.39 (1.04–1.87)	0.02791	0.94965
3-hydroxypyridine sulfate	0.68 (0.48–0.97)	0.03273	0.66 (0.49–0.89)	0.00648	0.91352
1-(1-enyl-oleoyl)-2-docosahexaenoyl-GPE (P-18:1/22:6)	1.65 (1.11–2.45)	0.0132	1.38 (1.06–1.79)	0.01634	0.41561
1-palmitoyl-GPC (16:0)	1.82 (1.30–2.55)	4.61×10−4	1.12 (0.81–1.56)	0.48253	0.03265
1-(1-enyl-palmitoyl)-GPC (P-16:0)	1.70 (1.19–2.43)	0.00346	1.21 (0.91–1.61)	0.18623	0.11854
quinate	0.76 (0.55–1.04)	0.08682	0.66 (0.49–0.89)	0.0068	0.47547
1-stearoyl-GPC (18:0)	1.98 (1.36–2.87)	3.25×10−4	1.11 (0.81–1.51)	0.52083	0.01361
methylmalonate (MMA)	1.53 (1.11–2.12)	0.00926	1.33 (0.95–1.86)	0.09316	0.54087
N-(2-furoyl) glycine	0.75 (0.52–1.07)	0.112	0.67 (0.49–0.92)	0.01453	0.64005
5alpha-pregnan-diol disulfate	1.52 (1.10–2.11)	0.01103	1.30 (0.98–1.72)	0.06981	0.41333
glutamate	1.31 (0.96–1.80)	0.08963	1.50 (1.08–2.10)	0.01665	0.54464
cysteine	0.77 (0.55–1.06)	0.10464	0.71 (0.52–0.95)	0.02192	0.69915

The covariates listed in Table 2 were included in the regression analysis.