Table 3 –
Results for the validation set by site and by Gleason grade group for all patients in each cohort and for the subgroup with CAI >0
| All patients | Patients with CAI >0 | ||||
|---|---|---|---|---|---|
|
|
|||||
| n | c index | n (%) | c index | Median CAI (IQR) | |
| Site | |||||
| UHCMC | 146 | 0.48 | 92 (63) | 0.59 | 0.08 (0.14) |
| WCMC | 79 | 0.56 | 31 (39) | 0.63 | 0.05 (0.05) |
| TCGA | 174 | 0.78 | 125 (72) | 0.90 | 0.07 (0.15) |
| UPenn | 350 | 0.56 | 163 (47) | 0.60 | 0.06 (0.18) |
| Gleason grade group | |||||
| 1 | 146 | 0.47 | 57 (39) | 0.52 | 0.04 (0.06) |
| 2 | 356 | 0.52 | 193 (54) | 0.66 | 0.04 (0.09) |
| 3 | 139 | 0.43 | 93 (67) | 0.51 | 0.11 (0.22) |
| 4 | 48 | 0.51 | 31 (65) | 0.62 | 0.14 (0.23) |
| 5 | 47 | 0.60 | 31 (66) | 0.57 | 0.13 (0.21) |
CAI = cribriform area index; IQR = interquartile range; TCGA = The Cancer Genome Atlas; UHCMC = University Hospitals Cleveland Medical Center; UPenn = University of Pennsylvania; WCMC = New York-Presbyterian/Weill Cornell Medical Center.