TABLE 1.
Baseline Characteristics of Uncomplicated Lower Tract UTI Patients by Index Antibiotic Agent, IBM® MarketScan® Commercial Database, 2006–2015a
| First-line agents | Non-first-line agents | Non-recommended agents | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Characteristic | Nitrofurantoin (%) N=271,189 |
TMP/SMX (%) N=322,052 |
Fluoroquinolone (%) N=497,279 |
Broad-spectrum β-lactam (%) N=12,491 |
Narrow-spectrum β-lactam (%) N=30,087 |
AMX/AMP (%) N=7,613 |
| Age, median (IQR), y | 30 (23–37) | 29 (22–37) | 32 (24–39) | 29 (20–36) | 29 (21–36) | 30 (23–37) |
| Age group, y | ||||||
| 18–24 | 30.8 | 35.3 | 27.1 | 39.1 | 36.2 | 30.0 |
| 25–29 | 17.0 | 15.5 | 15.8 | 13.7 | 16.7 | 18.7 |
| 30–34 | 17.2 | 15.8 | 16.8 | 15.9 | 16.7 | 19.0 |
| 35–39 | 17.6 | 16.6 | 19.2 | 16.0 | 15.6 | 17.4 |
| 40–44 | 17.5 | 16.8 | 21.0 | 15.3 | 14.7 | 14.9 |
| Region of residence | ||||||
| Northeast | 13.9 | 13.9 | 13.7 | 14.9 | 8.8 | 19.0 |
| Midwest | 21.0 | 29.0 | 21.8 | 16.3 | 23.3 | 25.1 |
| South | 41.5 | 40.6 | 45.7 | 55.3 | 29.9 | 40.8 |
| West | 23.6 | 16.5 | 18.8 | 13.5 | 38.0 | 15.0 |
| Provider type | ||||||
| Emergency medicine | 6.8 | 7.1 | 7.4 | 8.8 | 18.9 | 3.0 |
| Internal medicine | 11.3 | 13.3 | 16.8 | 13.7 | 10.3 | 18.2 |
| Family medicine / Pediatrics | 32.3 | 40.0 | 38.3 | 41.0 | 30.5 | 41.4 |
| OBGYN | 14.4 | 4.3 | 4.2 | 4.0 | 5.3 | 5.4 |
| MD / DO | 6.1 | 7.6 | 6.3 | 5.1 | 7.0 | 6.8 |
| Non-MD | 5.3 | 6.7 | 4.6 | 3.6 | 2.8 | 3.3 |
| Other | 20.4 | 17.7 | 19.4 | 21.8 | 23.0 | 19.4 |
| Missing | 3.2 | 3.3 | 3.1 | 2.0 | 2.3 | 2.5 |
| Outpatient Encounter | ||||||
| In-person b | 97.1 | 97.1 | 97.3 | 98.3 | 98.0 | 98.1 |
| Laboratory only | 2.9 | 2.9 | 2.7 | 1.7 | 2.0 | 1.9 |
| Initial receipt of urine tests | ||||||
| Urinalysis | 78.6 | 78.7 | 78.9 | 78.2 | 75.3 | 74.0 |
| Culture | 53.3 | 43.7 | 48.0 | 56.9 | 47.1 | 49.3 |
Abbreviations: AMX/AMP, amoxicillin or ampicillin; DO, doctor of osteopathic medicine; IQR, interquartile range; OBGYN, obstetrics and gynecology; TMP/SMX, trimethoprim-sulfamethoxazole.
a
Baseline covariates were assessed during the 180-day period prior to the index prescription.
b
Includes emergency department visits, office visits, phone call consultations, and online consultations.