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. 2021 Aug 23;12:738590. doi: 10.3389/fphar.2021.738590

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Copyright © 2021 Wu, Zhang, Zhou, Yang, Chen, Zhao, Zhong, Lin and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of clemastine on expression levels of WNT/β-catenin signaling pathway. (A) The differential expression of WNT10B was labeled in our previous sequencing results. (B) Relative mRNA expressions of WNT10B and β-catenin, normalized to that of the GAPDH internal control. (C) Representative western blot images of WNT10B and β-catenin. (D) Relative protein expressions of WNT10B and β-catenin, normalized to that of the β-tubulin internal control. The data are presented as mean ± S.D. (n = 10 mice per group). ***p < 0.005 compared with the CON group. ****p < 0.001 compared with the CON group. ^# p < 0.05 compared with the PND group. ^## p < 0.01 compared with the PND group. ^### p < 0.005 compared with the PND group. ^#### p < 0.001 compared with the PND group.