Table 3.

Haplotype frequencies and associations with pulmonary TB.

Haplotypesa	Frequency inPatientsb	Frequency inControls	P Valuec	PermutationP value
TLR2
insT	0.591	0.536	0.0732	0.6576
insC	0.244	0.289	0.0987	0.7665
delC	0.154	0.160	0.7951	1
delT	0.012	0.016	0.5744	1
TLR1-TLR6-TLR10
ATGTA	0.298	0.243	0.0485	0.4463
AGTCG	0.255	0.263	0.7784	1
ATGTG	0.170	0.215	0.0688	0.6201
AGGTG	0.110	0.121	0.5933	1
AGTTG	0.045	0.041	0.7844	1
GGTCG	0.044	0.028	0.1705	0.9125
ATTTG	0.030	0.033	0.7762	1
ATTCG	0.023	0.034	0.2712	0.9818
AGGTA	0.010	0.018	0.27	0.9816
VDR
CC	0.492	0.515	0.4556	1
AT	0.375	0.371	0.8939	1
AC	0.133	0.113	0.3484	0.9917

^aHaplotypes: TLR2 [rs111200466, rs3804099]; TLR1-TLR6-TLR10 [rs11466657, rs11096957, rs5743618, rs4833095, rs5743810]; VDR [rs7975232, rs1544410]

^bOnly haplotypes with a frequency > 0.01 were included in this table.

^CP Values were calculated using χ² test.

Bold: significant differences (nominal P value < 0.05) in haplotype distribution.