Table 4.
Association of combined genotypes TLR6 rs5743810 and TLR10 rs11096957 with pulmonary TB.
| Genotype |
Counts, n (%) |
Association (P value) |
OR (95% CI)a | |||
|---|---|---|---|---|---|---|
| TLR6 rs5743810 | TLR10 rs11096957 | Controls | Patients | Fisher test | Logistic regressiona | |
| GG | TT | 58 (23.8) | 56 (21.1) | 0.56 | 0.83 | 0.94 (0.60–1.47) |
| GG | GT | 57 (23.4) | 43 (16.2) | 0.059 | 0.033 | 0.61 (0.38–0.96) |
| GG | GG | 19 (7.8) | 16 (6.0) | 0.55 | 0.59 | 0.80 (0.37–1.72) |
| GA | TT | 7 (2.9) | 2 (0.8) | 0.14 | 0.094 | 0.25 (0.025–1.36) |
| GA | GT | 42 (17.2) | 91 (34.3) | 1.5 × 10−5 | 1.9 × 10−5 | 2.48 (1.62–3.85) |
| GA | GG | 42 (17.2) | 38 (14.3) | 0.45 | 0.34 | 0.79 (0.48–1.30) |
| AA | TT | 17 (7.0) | 18 (6.8) | 0.94 | 0.86 | 0.91 (0.43–1.91) |
| AA | GT | 2 (0.8) | 1 (0.4) | 0.94 | 0.60 | 0.45 (0.0077–8.86) |
a Adjusted for sex and age at recruitment.
Bold: significant association after Bonferroni correction (P value < 3.10945 × 10−5).