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. 2021 Aug 23;11:723481. doi: 10.3389/fcimb.2021.723481

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Copyright © 2021 Ackland, Heinson, Cleary, Christodoulides, Wilkinson and Staples

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Enrichment of macrophage immune responses during NTHi persistence. Enrichment analysis using ToppFunn identified over 500 significantly enriched biological processes which were clustered using EnrichmentMap and AutoAnnotate in Cytoscape to identify the key biological processes involved in the MDM response to NTHi. Nodes represent individual GO:terms, with size relating to the number of genes in each term and the colour indicating enrichment significance. Edges represent connections between nodes that share genes.