TABLE 1.
Optogenetic manipulations of NAc neurons.
|
Shown are the targeted neuron populations (Target), Opsin, NAc subregion (Site), optogenetic experimental parameters (Opsin), Frequency (Freq), Pulse width (Pulse), Light power (Power), and Stimulation (Pattern), behavioral task (Task), and behavioral effect (Effect; Increase:
, Decrease
:, No Effect:
). Reported values are from each reference (Ref), unless values were not reported (NR). Behavioral tasks include drug conditioned place preference (CPP), real-time place preference (RTPP), and intracranial self-stimulation (ICSS) to assess hedonic processing or positive reinforcement; progressive ratio (PR) operant schedule to assess motivation; lithium-chloride conditioned place aversion (LiCl CPA) to assess avoidance; 5-choice serial reaction time task (5-CSRTT) to assess impulsivity; and Pavlovian-to-instrumental transfer (PIT) to assess conditioned motivation.