TABLE 3.

Effect of oral and intraduodenal administration of ranitidine and (-)-Carveol in gastric ulcers induced by pyloric ligation in rats.

Treatment	Route of administration	Dose (mg/kg)	ULI	Inhibition (%)
5% Tween 80	Oral	—	366.6 ± 20.03
Ranitidine	Oral	50	162.7 ± 24.1***	55
(-)-Carveol	Oral	100	143.8 ± 14.8***	60
5% Tween 80	Intraduodenal	—	340.2 ± 16.9
Ranitidine	Intraduodenal	50	179.1 ± 25.3###	47
(-)-Carveol	Intraduodenal	100	132.4 ± 15.5###	61

The results are expressed as mean ± SD. One-way analysis of variance (ANOVA) followed by Dunnett’s test: ***p < 0.001 compared to the 5% tween 80 group orally and ^### p <0.001 compared to the 5% tween 80 group intraduodenal, (n = 8–10). ULI, Ulcerative Injury Index.