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. 2021 Aug 23;12:681974. doi: 10.3389/fendo.2021.681974

Figure 6.

Figure 6

HSD11B2 exosomal mRNA levels and steroid ratio and aldosterone and renin correlations in AME subjects (on the left) and in EH patients (on the right). 11β-HSD2 exosomal mRNA showed a positive correlation with THF+allo-THF/THE ratio in AME subjects, r = 0.6266, p-value = 0.0710 (A) and an inverse correlation in EH patients, r = −0.07793, p-value = 0.8420 (B). Similar trend was found between 11β-HSD2 exosomal mRNA and F/E ratio in AME, r = 0.7825, p-value = 0.0127 (C) and inverse in EH, r = −0.3762, p-value = 0.3184 (D). On the contrary, an inverse and significant correlation was found between 11β-HSD2 exosomal mRNA and aldosterone and renin in AME and a positive significance for renin in EH, r = −0.6921, p-value = 0.0388 (E) and r = −0.7649, p-value = 0.00164 (G), r = 0.692, p-value = 0.039 (H), respectively. No correlation was found in EH for 11β-HSD2 exosomal mRNA and aldosterone, r = 0.081, p-value = 0.8359 (F).