Table 2.
The association between tRF-31-U5YKFN8DYDZDD expression and clinicopathologic parameters in 111 GC specimens.
| Parameters | Total | tRf-DZDD expression | P value | |
|---|---|---|---|---|
| Low (<median) | High (≥median) | |||
| Age | 0.504 | |||
| <60 | 37 | 12 | 25 | |
| ≥60 | 74 | 19 | 55 | |
| Gender | 0.518 | |||
| Male | 70 | 18 | 52 | |
| Female | 41 | 13 | 28 | |
| Differentiation grade | 0.527 | |||
| Well-moderate | 49 | 12 | 37 | |
| Poor-undifferentiation | 62 | 19 | 43 | |
| Tumor size | 0.078 | |||
| <5 cm | 70 | 24 | 46 | |
| ≥5 cm | 41 | 7 | 34 | |
| Depth of invasion | 0.016* | |||
| T1–T2 | 43 | 18 | 25 | |
| T3–T4 | 68 | 13 | 55 | |
| Lymph node metastasis | 0.010* | |||
| Negative | 46 | 19 | 27 | |
| Positive | 65 | 12 | 53 | |
| TNM stage | 0.003** | |||
| I–II | 53 | 22 | 31 | |
| III–IV | 58 | 9 | 49 | |
| Lauren classification | 0.907 | |||
| Intestinal type | 32 | 8 | 24 | |
| Diffuse type | 34 | 10 | 24 | |
| Mixed type | 45 | 13 | 32 | |
| Nerve invasion | 0.668 | |||
| Negative | 67 | 20 | 47 | |
| Positive | 44 | 11 | 33 | |
| Vascular invasion | 0.033* | |||
| Negative | 46 | 18 | 28 | |
| Positive | 65 | 13 | 52 | |
| C-erbB-2 | 0.113 | |||
| Negative | 102 | 26 | 76 | |
| Positive | 9 | 5 | 4 | |
| CEA | 0.833 | |||
| Negative (<5 ng/ml) | 48 | 14 | 34 | |
| Positive (≥5 ng/ml) | 63 | 17 | 46 | |
| CA199 | 0.385 | |||
| Negative (<37 U/ml) | 71 | 22 | 49 | |
| Positive (≥37 U/ml) | 40 | 9 | 31 | |
| CA724 | 0.831 | |||
| Negative (<10 U/ml) | 46 | 19 | 46 | |
| Positive (≥10 U/ml) | 65 | 12 | 34 | |
Statistical analyses were performed by the Pearson χ2 test.
*P < 0.05, **P < 0.01 was considered significant.