Table 3.
Multivariate Cox regression analysis of tRF-31-U5YKFN8DYDZDD and clinical variables predicting survival from 111 GC specimens.
| Parameter | Relative ratio | 95% CI | P Value |
|---|---|---|---|
| Age (<60 vs. ≥60) | 0.608 | 0.355–1.042 | .070 |
| Gender (Male vs. Female) | 1.204 | 0.720–2.015 | .479 |
| Differentiation grade (Well-moderate vs. Poor-undifferentiation) | 0.806 | 0.449–1.447 | .470 |
| Tumor size (<5 vs. ≥5 cm) | 0.814 | 0.471–1.405 | .459 |
| Depth of invasion (T1–T2 vs. T3–T4) | 1.429 | 1.032–1.979 | .032* |
| Lymph node metastasis (Negative vs. Positive) | 1.459 | 0.671–3.171 | .340 |
| TNM stage (I–II vs. III–IV) | 0.399 | 0.162–.984 | .046* |
| Lauren classification (Intestinal type vs. Diffuse type vs. Mixed type) | 0.897 | 0.457–1.760 | .752 |
| Nerve invasion (Negative vs. Positive) | 1.719 | 0.915–3.230 | .092 |
| Vascular invasion (Negative vs. Positive) | 0.574 | 0.308–1.068 | .080 |
| C-erbB-2 (Negative vs. Positive) | 1.329 | 0.430–4.107 | .621 |
| CEA (<5 vs. ≥5 ng/ml) | 0.690 | 0.406–1.173 | .171 |
| CA199 (<37 vs. ≥37 U/ml) | 0.865 | 0.507–1.476 | .595 |
| CA724 (<10 vs. ≥10 U/ml) | 1.381 | 0.813–2.347 | .232 |
| tRF-31-U5YKFN8DYDZDD (Negative vs. Positive) | 4.179 | 2.143–8.149 | .001** |
*P < 0.05, **P < 0.01 was considered significant.