Table 4.
Use the expression levels of tRF-31-U5YKFN8DYDZDD, CEA, CA199, and CA724 to distinguish GC patients from healthy donors.
| SEN, % | SPE, % | ACCU, % | PPV, % | NPV, % | |
|---|---|---|---|---|---|
| tRF-DZDD | 60.36 (67/111) | 80.90 (72/89) | 69.50 (139/200) | 79.76 (67/84) | 62.07 (72/116) |
| CEA | 57.66 (64/111) | 67.42 (60/89) | 62.00 (124/200) | 68.82 (64/93) | 56.07 (60/107) |
| CA199 | 36.04 (40/111) | 82.02 (73/89) | 56.50 (113/200) | 71.43 (40/56) | 50.69 (73/144) |
| CA724 | 42.34 (47/111) | 74.16 (66/89) | 56.50 (113/200) | 67.14 (47/70) | 50.77 (66/130) |
| tRF-DZDD+CEA | 68.47 (76/111) | 79.78 (71/89) | 73.50 (147/200) | 80.85 (76/94) | 66.98 (71/106) |
| tRF-DZDD+CA199 | 71.17 (79/111) | 73.03 (65/89) | 72.00 (144/200) | 76.70 (79/103) | 67.01 (65/97) |
| tRF-DZDD+CA724 | 63.96 (71/111) | 80.90 (72/89) | 71.50 (143/200) | 80.68 (71/88) | 64.29 (72/112) |
| tRF-DZDD+CEA+CA199 | 72.97 (81/111) | 78.65 (70/89) | 75.50 (151/200) | 81.00 (81/100) | 70.00 (70/100) |
| tRF-DZDD+CEA+CA724 | 66.67 (74/111) | 83.15 (74/89) | 74.00 (148/200) | 83.15 (74/89) | 66.67 (74/111) |
| tRF-DZDD+ CA199+CA724 | 74.77 (83/111) | 74.16 (66/89) | 74.50 (149/200) | 78.30 (83/106) | 70.21 (66/94) |
| tRF-DZDD+CEA+ CA199+CA724 | 81.98 (91/111) | 69.66 (62/89) | 76.50 (153/200) | 77.12 (91/118) | 75.61 (62/82) |
SEN, sensitivity; SPE, specificity; ACCU, overall accuracy; PPV, positive predictive value; NPV, negative predictive value.