Table 5.
Use the expression levels of tRF-31-U5YKFN8DYDZDD, CEA, CA199, and CA724 to distinguish GC patients from gastritis patients.
| SEN, % | SPE, % | ACCU, % | PPV, % | NPV, % | |
|---|---|---|---|---|---|
| tRF-DZDD | 58.56 (65/111) | 72.92 (35/48) | 62.89 (100/159) | 83.33 (65/78) | 43.21 (35/81) |
| CEA | 57.66 (64/111) | 62.50 (30/48) | 59.12 (94/159) | 78.05 (64/82) | 38.96 (30/77) |
| CA199 | 36.04 (40/111) | 70.83 (34/48) | 46.54 (74/159) | 74.07 (40/54) | 32.38 (34/105) |
| CA724 | 42.34 (47/111) | 68.75 (33/48) | 50.31 (/15980) | 75.81 (47/62) | 34.02 (33/97) |
| tRF-DZDD+CEA | 59.46 (66/111) | 68.75 (33/48) | 62.26 (99/159) | 81.48 (66/81) | 42.31 (33/78) |
| tRF-DZDD+CA199 | 81.98 (91/111) | 47.92 (23/48) | 71.70 (114/159) | 78.45 (91/116) | 53.49 (23/43) |
| tRF-DZDD+CA724 | 62.16 (69/111) | 68.75 (33/48) | 64.15 (102/159) | 82.14 (69/84) | 44.00 (33/75) |
| tRF-DZDD+CEA+CA199 | 86.49 (96/111) | 45.83 (22/48) | 74.21 (118/159) | 78.69 (96/122) | 59.46 (22/37) |
| tRF-DZDD+CEA+CA724 | 81.08 (90/111) | 50.00 (24/48) | 71.70 (114/159) | 78.95 (90/114) | 53.33 (24/45) |
| tRF-DZDD+ CA199+CA724 | 72.97 (81/111) | 62.50 (30/48) | 69.81 (111/159) | 81.82 (81/99) | 50.00 (30/60) |
| tRF-DZDD+CEA+ CA199+CA724 | 86.49 (96/111) | 47.92 (23/48) | 74.84 (119/159) | 79.34 (96/121) | 60.53 (23/38) |
SEN, sensitivity; SPE, specificity; ACCU, overall accuracy; PPV, positive predictive value; NPV, negative predictive value.