Table 1.
Pretreatment clinical characteristics of LAGC (cT4NxM0) patients before 1:1 matched.
| Characteristics | Total (N = 902) | NAC (n = 285) | S (n = 617) | P |
|---|---|---|---|---|
| Sex (n[%]) | 0.050* | |||
| Male | 618 (68.51) | 208 (72.98) | 410 (66.45) | |
| female | 284 (31.49) | 77 (27.02) | 207 (33.55) | |
| Age (y) | 0.624§ | |||
| Median (range) | 62 (21-80) | 63 (21-80) | 62 (26-80) | |
| BMI (kg/m2) | 0.358# | |||
| Median (range) | 22.80 (13.97-33.20) | 22.91 (14-33.20) | 22.72 (13.97-32.89) | |
| Hemoglobin (g/L) | 0.446§ | |||
| Median (range) | 124 (44-184) | 123 (44-164) | 124 (45-184) | |
| Leukocyte (10^9/L) | 0.200§ | |||
| Median(range) | 5.70 (2.20-16.90) | 5.70 (2.40-16.90) | 5.70 (2.20-14.93) | |
| Platelet (10^9/L) | 0.034§ | |||
| Median (range) | 216 (41-924) | 223 (82-924) | 211 (41-754) | |
| Prealbumin (g/L) | 0.192* | |||
| Median (range) | 208 (67-388) | 206 (79-354) | 211 (67-388) | |
| Total Protein (g/L) | 0.990§ | |||
| Median (range) | 65 (41-82) | 64 (46-78) | 65 (41-82) | |
| Albumin (g/L) | 0.040§ | |||
| Median (range) | 37 (21-48) | 37 (21-47) | 37 (21-48) | |
| CA125 (U/mL) | 0.001§ | |||
| Median (range) | 10.90 (1.20-601.80) | 12.10 (2.19-314.10) | 10.25 (1.20-601.80) | |
| CA199 (U/mL) | 0.646§ | |||
| Median (range) | 8.20 (0.80-20830) | 8 (0.80-7424) | 8.20 (0.80-20830) | |
| CA724 (U/mL) | 0.005§ | |||
| Median (range) | 2.33 (0.06-300) | 3.19 (0.06-300) | 2.14 (0.20-300) | |
| CEA (ng/mL) | 0.002§ | |||
| Median (range) | 2.24 (0.50-1803.83) | 2.42 (0.50-1400.45) | 2.16 (0.50-1803.83) | |
| AFP (ng/mL) | 0.760§ | |||
| Median (range) | 2.55 (0.50-10783.52) | 2.54 (0.65-10783.52) | 2.56 (0.50-9017.75) | |
| Differentiation (n[%]) | 0.002* | |||
| Well | 332 (36.81) | 126 (44.21) | 206 (33.39) | |
| poor | 570 (63.19) | 159 (55.79) | 411 (66.61) | |
| Signet ring cell (n[%]) | <0.001* | |||
| Yes | 304 (33.70) | 60 (21.05) | 244 (39.55) | |
| No | 598 (66.30) | 225 (78.95) | 373 (60.45) | |
| Borrmann (n[%]) | 0.004* | |||
| I/II | 89 (9.87) | 16 (5.61) | 73 (11.83) | |
| III/IV | 813 (90.13) | 269 (94.39) | 544 (88.17) | |
| cN stage (n[%]) | <0.001* | |||
| 0-1 | 404 (44.79) | 61 (21.40) | 343 (55.59) | |
| 2 | 366 (40.58) | 139 (48.77) | 227 (36.79) | |
| 3 | 132 (14.63) | 85 (29.82) | 47 (7.62) |
*χ2 test (compares the counts of categorical responses between 2 or more independent groups).
§Mann-Whitney rank test (a nonparametric alternative to the 2 sample t test compares the means of 2 independent groups).
#T test (compare the means of 2 independent groups).