Table 2.
Pre-treatment clinical characteristics of LAGC (cT4NxM0) patients after 1:1 matched.
| Characteristics | Total (N = 442) | NAC (n = 221) | S (n = 221) | P |
|---|---|---|---|---|
| Sex (n[%]) | 0.443* | |||
| Male | 331 (74.89) | 162 (73.30) | 169 (76.47) | |
| female | 111 (25.11) | 59 (26.70) | 52 (23.53) | |
| Age (y) | 0.350§ | |||
| Median (range) | 62.50 (21-80) | 63 (21-80) | 61 (36-80) | |
| BMI (kg/m2) | 0.741# | |||
| Median (range) | 22.90 (14-33.20) | 22.84 (14-33.20) | 22.99 (14.98-31.59) | |
| Hemoglobin (g/L) | 0.413§ | |||
| Median (range) | 123 (44-173) | 125 (44-164) | 121 (45-173) | |
| Leukocyte (10^9/L) | 0.251§ | |||
| Median(range) | 5.80 (2.30-16.90) | 5.70 (2.70-16.90) | 5.80 (2.30-14.93) | |
| Platelet (10^9/L) | 0.311§ | |||
| Median (range) | 218.50 (56-875) | 216 (88-875) | 226 (56-754) | |
| Prealbumin (g/L) | 0.247# | |||
| Median (range) | 206.50 (92-366) | 203 (118-340) | 212 (92-366) | |
| Total Protein (g/L) | 0.953§ | |||
| Median (range) | 64 (41-82) | 64 (46-77) | 64 (41-82) | |
| Albumin (g/L) | 0.712§ | |||
| Median (range) | 37 (21-48) | 37 (21-47) | 37 (21-48) | |
| CA125 (U/mL) | 0.111§ | |||
| Median (range) | 10.95 (2.19-465.20) | 11.60 (2.19-314.10) | 10.40 (2.90-465.20) | |
| CA199 (U/mL) | 0.488§ | |||
| Median (range) | 9.45 (0.80-7424) | 8.70 (0.80-7424) | 10.1 (0.80-3842.20) | |
| CA724 (U/mL) | 0.419§ | |||
| Median (range) | 2.83 (0.46-300) | 3.36 (0.46-300) | 2.43 (0.66-300) | |
| CEA (ng/mL) | 0.356§ | |||
| Median (range) | 2.40 (0.50-1400.45) | 2.42 (0.50-1400.45) | 2.38 (0.50-930.43) | |
| AFP (ng/mL) | 0.326§ | |||
| Median (range) | 2.60 (0.77-9017.75) | 2.46 (0.90-3220.19) | 2.66 (0.77-9017.75) | |
| Differentiation (n[%]) | 0.702* | |||
| Well | 196 (44.34) | 100 (45.25) | 96 (43.44) | |
| poor | 246 (55.66) | 121 (54.75) | 125 (56.56) | |
| Signet ring cell (n[%]) | 0.586* | |||
| Yes | 113 (25.57) | 54 (24.43) | 59 (26.70) | |
| No | 329 (74.43) | 167 (75.57) | 162 (73.30) | |
| Borrmann (n[%]) | 0.208* | |||
| I/II | 24 (5.43) | 15 (6.79) | 9 (4.07) | |
| III/IV | 418 (94.57) | 206 (93.21) | 212 (95.93) | |
| cN stage (n[%]) | 0.742* | |||
| 0-1 | 118 (26.70) | 57 (25.79) | 61 (27.60) | |
| 2 | 244 (55.20) | 126 (57.01) | 118 (53.39) | |
| 3 | 80 (18.10) | 38 (17.19) | 42 (19.01) |
*χ2 test (compares the counts of categorical responses between 2 or more independent groups).
§Mann-Whitney rank test (a nonparametric alternative to the 2 sample t test compares the means of 2 independent groups).
#T test (compare the means of 2 independent groups).