TABLE 11.

Alignment of segment 600–628 from various genotypes of HCV. In bold are represented the highly conserved residues. In green, amino acids modified by mutagenesis. In red, aromatic residues.

Genotype	Sequence
HCV1a (H77)	GPRITPRCMVDYPYRLWHYPCTINYTIFK
HCV1b (BK)	GPWLTPRCMVDYPYRLWHYPCTVNFTIFK
HCV2a (BEBE1)	GPWLTPRCLVDYPYRLWHYPCTVNYTIYK
HCV5a (SA13)	GPWVTPRCLVDYPYRLWHYPCTVNFTVHK
HCV3a (NZL1)	GPWLTPRCMVDYPYRLWHYPCTVDFRLFK
HCV6a (6a33)	GPWLTPRCLVHYPYRLWHYPCTLNYTIFK
HCV4a (ED43)	GPWITPRCLIDYPYRLWHFPCTANFSVFN