TABLE 6.

Alignment of segment 314–342 from various genotypes of HCV (Spadaccini et al., 2010). In bold are represented the highly conserved residues. In red and blue are the α-helices (319–323) and (329–338) respectively.

Genotype	Sequence
HCV1a (H77)	TGHRMAWNMMMNWSPTAALVVAQLLRIPQ
HCV1b (BK)	SGHRMAWDMMMNWSPTTALVVSQLLRIPQ
HCV2a (BEBE1)	TGHRMAWDMMMNWSPTTTMLLAYLVRIPE
HCV5a (SA13)	TGHRMAWDMMMNWSPTTALVMAQLLRIPQ
HCV3a (NZL1)	SGHRMAWDMMMNWSPAVGMVVAHVLRLPQ
HCV6a (6a33)	TGHRMAWDMMMSWSPTTTLVLSSILRVPE
HCV4a (ED43)	TGHRMAWDMMMNWSPTTTLVLAQVMRIPT