FIGURE 2.

DL-NBP treatment ameliorates renal injury in db/db mice. (A,B) BUN and Cr levels in serum from db/m mice, db/db mice, and DL-NBP treated mice (db/db mice were treated with 20, 60, or 120 mg⋅kg⁻¹ d⁻¹ of DL-NBP) (n = 8). (C–E) Representative images and quantification of H&E, Masson’s trichrome, and PAS staining (original magnification × 400) in kidney of mice from each group (n = 3), Scale bar = 20 μm. Data are presented as the mean ± SEM; **p < 0.01, ***p < 0.001 vs. db/m control mice; ^# p < 0.05, ^## p < 0.01, ^### p < 0.001 vs. db/db mice. BUN, blood urea nitrogen; Cr, creatinine; H&E, hematoxylin and eosin.