Table 2.
Laboratory results at admission and when HFNC was started.
| Total |
Only HFNC |
HFNC + IMV |
p-value | |
|---|---|---|---|---|
| N = 378 | n = 270 | n = 108 | ||
| Creatinine (mg/dl), n = 353 | ||||
| At admission | 0.9 (0.7–1.0) | 0.8 (0.7–1.0) | 0.9 (0.8–1.2) | 0.002 |
| At HFNC start | 0.8 (0.7–1.0) | 0.8 (0.7–1.0) | 0.8 (0.6–1.2) | 0.85 |
| FiO2 (mmHg), n = 348 | ||||
| At admission | 35 (24–56) | 35 (24–53) | 32 (24–60) | 0.82 |
| At HFNC start | 45 (32–75) | 40 (30–60) | 63 (34–94) | <0.0001 |
| Lymphocyte (%) n = 362 | ||||
| At admission | 11.7 (6.9–18.6) | 12.4 (7.7–18.6) | 10.6 (6.3–17.4) | 0.06 |
| At HFNC start | 11.5 (7.4–19.1) | 12.5 (8.0–20.7) | 8.8 (5.5–16.1) | <0.0001 |
| D-dimer (ng/ml), n = 357 | ||||
| At admission | 550 (380–890) | 555 (390–940) | 550 (360–790) | 0.32 |
| At HFNC start | 580 (370–970) | 540 (350–860) | 735 (490–1145) | <0.0001 |
| Ferritin (µg/l), n = 279 | ||||
| At admission | 466.6 (227.3–836.8) | 466.6 (229.2–770.6) | 467.8 (219.8–961.7) | 0.69 |
| At HFNC start | 457.4 (249.9–780.7) | 438.4 (230.5–714.1) | 556.4 (305.2–971.7) | 0.03 |
Data are presented as median (interquartile range).
FiO2, fraction of inspired oxygen; HFNC, high-flow nasal cannula; IMV, invasive mechanical ventilation.