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. 2021 Aug 27;36(4):745–756. doi: 10.3803/EnM.2021.405

Table 1.

Summary on the Changes in Hormonal Circadian Rhythm after Intermittent Fasting in Wildtype Rodents

Hormone Study Strain (sex, n) Type (duration) Changes after intervention

Mean level Acrophase shift
Insulin Duan et al. (2003) [39] C57BL/6 mouse (male, 8–10) ADF (3 months) ND
Anson et al. (2003) [40] C57BL/6 mouse (male, 8) ADF (20 weeks) ND
Rubin et al. (1988) [41] Sprague-Dawley rat (male, 36 or 48) TRF (3 weeks) 9:30 PM → 12:00–1:00 PM

Corticosterone Morimoto et al. (1977) [76]a Sprague-Dawley rat (female, 4 in each sampling time) TRF (14 days) ND 8:00 PM → 12:00 PM
Wilkinson et al. (1979) [77] Sprague-Dawley rat (male, 6–8 in each sampling time) TRF (20 days) Unchanged 9:00 PM → 9:00 AM

ADF, alternate-day fasting; ND, not determined; TRF, time-restricted feeding.

a

Among three types of experiments, this review summarized the result obtained from Experiment III.