. 2021 Aug 10;36(4):778–789. doi: 10.3803/EnM.2021.1101

Table 4.

Stratified Relationships between SCH and Blood Pressure Parameters in Subjects Grouped by Age and Sex

	Number	HTN	S1-HTN	S2-HTN	SBP	DBP	PP	MAP
Male subjects aged <65 yr
Euthyroid	23,732	Reference	Reference	Reference	Reference	Reference	Reference	Reference
SCH Model 1	2,706	1.185 (1.093–1.284)^a	1.108 (1.019–1.204)^b	1.119 (1.017–1.231)^b	0.74±0.30^b	0.86±0.23^a	−0.12±0.24	0.82±0.23^a
SCH Model 2	2,706	1.138 (1.046–1.237)^a	1.090 (1.002–1.186)^b	1.063 (0.963–1.174)	0.27±0.29	0.64±0.22^a	−0.37±0.24	0.52±0.22^b

Female subjects aged <65 yr
Euthyroid	22,303	Reference	Reference	Reference	Reference	Reference	Reference	Reference
SCH Model 1	4,210	1.307 (1.221–1.399)^a	1.159 (1.074–1.252)^a	1.381 (1.254–1.521)^a	2.33±0.26^a	1.42±0.17^a	0.91±0.20^a	1.73±0.18^a
SCH Model 2	4,210	1.213 (1.130–1.303)^a	1.103 (1.021–1.192)^b	1.261 (1.140–1.394)^a	1.44±0.24^a	1.02±0.16^a	0.42±0.19^b	1.16±0.17^a

Male subjects aged ≥65 yr
Euthyroid	1,836	Reference	Reference	Reference	Reference	Reference	Reference	Reference
SCH Model 1	384	0.842 (0.665–1.067)	0.944 (0.740–1.205)	0.903 (0.721–1.130)	−0.89±1.07	0.39±0.68	−1.28±0.91	−0.04±0.71
SCH Model 2	384	0.787 (0.618–1.003)	0.941 (0.735–1.203)	0.859 (0.683–1.079)	−1.43±1.06	0.16±0.67^a	−1.59±0.91	−0.37±0.70

Female subjects aged ≥65 yr
Euthyroid	1,562	Reference	Reference	Reference	Reference	Reference	Reference	Reference
SCH Model 1	419	1.254 (0.991–1.586)	1.382 (1.092–1.750)^a	0.933 (0.749–1.163)	−0.16±1.06	1.55±0.66^b	−1.71±0.93	0.98±0.69
SCH Model 2	419	1.270 (0.999–1.615)	1.394 (1.100–1.766)^a	0.931 (0.743–1.165)	−0.09±1.05	1.55±0.65^b	−1.65±0.93	1.01±0.67

Values are expressed as odds ratio (95% confidence interval) or linear regression coefficient±standard deviation. Model 1: crude; Model 2: adjusted for education level, residence, smoking frequency, daily salt intake, body mass index, and diabetes.

SCH, subclinical hypothyroidism; HTN, hypertension; S1-HTN, stage 1 hypertension; S2-HTN, stage 2 hypertension; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP, pulse pressure; MAP, mean arterial pressure.

P<0.01;

P<0.05.