Figure EV1. MiR‐342‐3p is associated with TB susceptibility.

• A
  Cell death mechanisms of C3H and B6 BMDMs after stimulation with Mtb for 36 h. Data are shown as the mean ± SEM of n = 3 biological replicates.
• B
  Relative miRNA expression was detected by qRT–PCR using miR‐342‐3p specific primer. Data are shown as the mean ± SEM of n = 3 biological replicates.
• C, D
  Cell death mechanisms of C3H BMDMs transfected with miR‐342‐3p mimic (C), or B6 BMDMs transfected with miR‐342‐3p inhibitor (D), followed by Mtb infection for 36 h. Representative data (from n = 3 biological replicates) are shown as the mean ± SEM of technical replicates.
• E, F
  Cell death mechanisms of C3H BMDMs transfected with miR‐342‐3p inhibitor (E), or B6 BMDMs transfected with miR‐342‐3p mimic (F), followed by Mtb infection for 36 h. Data are shown as the mean ± SEM of n = 3 biological replicates.
• G, H
  Mtb growth rates of C3H BMDMs transfected with miR‐342‐3p inhibitor (G), or B6 BMDMs transfected with miR‐342‐3p mimic (H) after Mtb infection. Data are shown as the mean ± SEM of n = 3 biological replicates.
• I, J
  Cell death mechanisms of C3H BMDMs transfected with miR‐342‐5p mimic (I), or B6 BMDMs transfected with miR‐342‐5p inhibitor (J), followed by Mtb infection for 36 h. Data are shown as the mean ± SEM of n = 3 biological replicates.

Data information: ANOVA followed by Bonferroni post hoc test was used for data analysis (A, B, E‐J). *P < 0.05, **P < 0.01. Abbreviation: n.s., not significant. NC, negative control.

Source data are available online for this figure.