Figure 7. The increased expression of RAB7 rescues the phagosomes accumulation in NimB4sk2 macrophages.

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A–BRepresentative fluorescence microscopy images of wild‐type (A) or NimB4sk2 (B) macrophages expressing Rab5 (middle panel) or Rab7 (right panel) driven by HmlΔ‐Gal4 and stained with the LysoTracker Red (live imaging). Overlay of fluorescence and DIC. Scale bar = 10 μm.
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CQuantification of the mean fluorescence intensity of LysoTracker in macrophages from larvae (confocal live imaging). Values from at least three independent experiments are represented as mean ± SD (**P < 0.01, ****P < 0.0001 by ANOVA test followed by post hoc Dunnett's multiple comparison tests. ns: not significant).