TABLE 3.

Average annual crude SCC head and neck cancers incidence rates and trends HPV‐related sites (2000–2016)

HPV‐related sites	Average annual rate (per 100,000)	Slope 1	Slope 2
		Years	APC	Years	APC
Total	10.8 (10.7–11.0)	2000–2006	2.92*	2006–2016	7.90*
Sex
Males	19.1 (18.8–19.4)	2000–2006	4.53*	2006–2016	8.82*
Females	4.4 (4.3–4.6)	2000–2007	−0.34	2007–2016	4.91*
Race
Black	10.2 (9.7–10.7)	2000–2016	4.15*
White	11.6 (11.4–11.8)	2000–2006	2.55	2006–2016	8.19*
Sex and Race
White males	20.2 (19.9–20.6)	2000–2006	4.20*	2006–2016	9.20*
White females	4.8 (4.6–4.9)	2000–2016	2.68*
Black males	19.8 (18.7–20.9)	2000–2016	4.78*
Black females	3.8 (3.4–4.2)	2000–2016	2.76*

^*Indicates that the annual percent change (APC) is significantly different from zero at the alpha = 0.05 level.