TABLE 4.

Average Annual Crude SCC Head and Neck Cancers Incidence Rates and Trends Stratified by Birth Cohort (2000–2016)

Birth cohort	Average annual rate (per 100,000)	Slope 1		Slope 2
		Years	APC	Years	APC
Non‐HPV related
Age 65–69	30.6 (30.1–31.1)	2000–2003	−5.71*	2003–2016	−1.68*
Age 70–74	35.3 (34.6–35.8)	2000–2016	−1.64*
Age 75–79	36.4 (35.7–37.0)	2000–2003	−5.27*	2003–2016	−0.33
Age 80+	33.5 (33.0–34.0)	2000–2016	−0.35
HPV related
Age 65–69	14.2 (13.9–14.5)	2000–2016	8.38*
Age 70–74	12.6 (12.3–13.0)	2000–2006	1.51	2006–2016	8.54*
Age 75–79	10.1 (9.7–10.4)	2000–2016	4.08*
Age 80+	11.7 (11.2–12.3)	2000–2016	4.62*

^*Indicates that the annual percent change (APC) is significantly different from zero at the alpha = 0.05 level.