TABLE 1.
Summary of baseline patient and tumor characteristics and mutational analyses
| Variable, n (%) | All patients (N=110) |
|---|---|
| Age, yearsa | 65.5 (12.5) |
| Gender | |
| Male | 31 (28.2) |
| Female | 79 (71.9) |
| Smoking status | |
| Smoker | 9 (8.2) |
| Ex‐smoker (1–5 years ago) | 11 (10.0) |
| Ex‐smoker (6–10 years ago) | 3 (2.7) |
| Ex‐smoker (>10 years ago) | 19 (17.3) |
| Never | 68 (61.8) |
| ECOG | |
| 0 | 50 (45.5) |
| 1 | 50 (45.5) |
| 2 | 8 (7.3) |
| Not available | 2 (1.8) |
| Stage M (at primary tumor diagnosis) | |
| M0 | 13 (11.8) |
| M1 | 97 (88.2) |
| Metastasis location | |
| M1a | 28 (25.5) |
| M1b | 78 (74.5) |
| Number of metastatic locations | |
| 1 | 56 (50.9) |
| ≥2 | 54 (49.1) |
| Tissue biopsy | |
| Primary tumor | 85 (77.3) |
| Metastasis | 25 (22.7) |
| EGFR mutation (tissue) | |
| Ex19del | 71 (64.5) |
| L858R | 39 (35.5) |
| p.T790 M mutation (tissue) | |
| Present | 1 (0.9) |
| Absent | 51 (46.4) |
| Not evaluated | 58 (52.7) |
| Progression type | |
| Extrapulmonary | 22 (38.6) |
| Pulmonary | 17 (29.8) |
| Both | 14 (24.6) |
| Not available | 4 (7.0) |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; SD, standard deviation.
a
Data are presented as mean (SD).