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. 2021 Aug 5;10(17):5765–5774. doi: 10.1002/cam4.4107

TABLE 3.

FI and TBFI 6‐month mortality rates by frailty level

Variable FI: 6‐month mortality TBFI: 6‐month mortality
OR (95% CI) p Value OR (95% CI) p Value
Age
<62 years 1.0 (Reference) 1.0 (Reference)
≥62 years 0.417 (0.206, 0.818) 0.0126 0.534 (0.269, 1.041) 0.0689
Sex
Female 1.0 (Reference) 1.0 (Reference)
Male 2.168 (1.058, 4.550) 0.0370 1.929 (0.956, 3.979) 0.0699
Type of primary cancer
Breast 1.0 (Reference) 1.0 (Reference)
GI 2.420 (0.753, 8.421) 0.1480 2.381 (0.744, 8.188) 0.1528
GU 1.204 (0.284, 5.230) 0.8012 2.114 (0.538, 8.696) 0.2885
H&N 1.609 (0.284, 9.265) 0.5877 2.485 (0.464, 14.041) 0.2891
Lung 2.174 (0.636, 7.886) 0.2232 3.335 (1.035, 11.592) 0.0489
Melanoma 3.241 (0.579, 19.848) 0.1865 3.683 (0.654, 22.741) 0.1450
Other 1.461 (0.365, 5.993) 0.5926 2.301 (0.613, 9.097) 0.2223
Group FI
Non‐frail 1.0 (Reference) 1.0 (Reference)
Mild 2.011 (0.884, 4.680) 0.0989 2.594 (0.793, 9.709) 0.1307
Moderate 5.506 (2.066, 15.469) 0.0008 4.610 (1.440, 17.040) 0.0140
Severe 10.967 (3.974, 33.236) <0.0001 9.725 (2.853, 38.501) 0.0005

Multivariable Logistic Regression Models for 6‐month mortality.

Abbreviations: FI, frailty index; GI, gastrointestinal; GU, genitourinary; H&N, head and neck; HR, hazard ratio; OS, overall survival.