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. 2021 Sep 6;22:227. doi: 10.1186/s13059-021-02449-1

Table 2.

Comparison of sequencing methods

OCEANS Standard NGS NGS w/ UMI
(MinION) (MiSeq) (MiSeq)
Samples / flow cell 24 24 2
Flow cell price <DOLLAR/>900 <DOLLAR/>1300 <DOLLAR/>1300
Flow cell reusability 10 1 1
Library preparation kits price <DOLLAR/>890 <DOLLAR/>750 <DOLLAR/>63
Sequencing price / sample <DOLLAR/>7.45 <DOLLAR/>85.4 <DOLLAR/>682
Turnaround time 10 h 24-72 h 24–72 h
Single-base VAF LoD 0.05–1% 2–5% 0.1–0.5%